COMBINE

COMBINE

Coordinating standards for modeling in biology

The “COmputational Modeling in BIology NEtwork” (COMBINE) is an initiative to coordinate the development of the various community standards and formats for computational models. By doing so, it is expected that the federated projects will develop a set of interoperable and non-overlapping standards covering all aspects of modeling in biology. The global COMBINE effort is led by the COMBINE Coordination Board.

Building on the experience of mature projects, which already have stable specifications, software support, user-base and community governance, COMBINE will help foster or support fledgling efforts aimed at filling gaps or new needs. As those efforts mature, they may become part of the core set of COMBINE standards.

One of the initial activities of COMBINE is to coordinate the organization of scientific and technical events common to several standards. Those events, as others related to our field of research are gathered in a calendar.

To discuss the goals, organization and operation of COMBINE, subscribe to COMBINE discuss mailing list.

To report issues about the co.mbine.org website, send a mail to combine-support @ googlegroups.com

Coordination

Coordinators

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Chris Myers

SBOL Delegate

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Sarah Keating

SBML Delegate

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David Nickerson

CellML Delegate (Chair)

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Falk Schreiber

SBGN Delegate

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Gary Bader

BioPAX Delegate

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Goksel Misirli

SBOL Visual Delegate

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Martin Golebiewski

Data Processing and Integration

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Matthias König

SED-ML Delegate

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Padraig Gleeson

NeuroML Delegate (Vice Chair)

Past Coordinators

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Dagmar Waltemath

Semantic Annotation Delegate

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Michael Hucka

SBML Delegate

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Nicolas Le Novere

Past Delegate

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Thomas Gorochowski

SBOL Visual Delegate

Upcoming Conferences

HARMONY 2026

Conference Date

2 - 5 February 2026

Conference Location

University of Auckland, Auckland, New Zealand

Important Dates

Registration closing date (in-person)
12th January 2026

Registration closing date (virtual)
2nd February 2026

Breakouts and tutorials submission deadline
8th January 2026

Notification of acceptance for breakout and tutorials
12th January 2026

Lightning talk and poster submission deadline
8th January 2026

Notification of acceptance for lightning talks and posters
12th January 2026

Important Links

combine logo

The “Computational Modeling in Biology” Network (COMBINE) is an initiative to coordinate the development of the various community standards and formats in systems biology, synthetic biology and related fields. HARMONY is a codefest-type meeting, with a focus on development of the standards, interoperability and infrastructure. There are generally not many general discussions or oral presentations during HARMONY; instead, the time is devoted to allowing hands-on hacking and interaction between people focused on practical development of software and standards.

HARMONY 2026 will be held at the University of Auckland.

Local organizers are David Nickerson, Weiwei Ai, Jarrah Dowrick, Alan Garny, and Hugh Sorby at the Auckland Bioengineering Institute.

Auckland Human Digital Twin Meetings 2026

From 2–12 Feb 2026, the Auckland Bioengineering Institute hosts three workshops in Auckland advancing digital twin modelling, interoperability standards, and clinical translation.

On this page you can find conference accommodation rates, venue and transport information for getting around Auckland, details on the other workshops happening during the same period, information about Waitangi Day — New Zealand’s national holiday, which falls during the meetings; as well as an optional Waiheke Island excursion and plenty of things to do and places to dine around the city.

Workshop Location

HARMONY 2026 will be held at the University of Auckland. It will be co-located with the 2026 Cardiopulmonary Physiome Workshop.

Draft Schedule

draft schedule

Arrival and Transportation

Getting from Auckland Airport (AKL) to the central city (also known as the ‘CBD’) is straightforward. Your main options depend on your budget, time, and preference for convenience.

Quick Comparison Table

MethodApprox. Cost (1 Adult)Approx. TimeBest For
Public Transport~$6.5050 - 60 minsBudget
Express Bus (SkyDrive)~$1835 - 50 minsSimplicity & Value
Ride-Share (Uber)~$40 - $6525 - 45 minsOn-Demand Convenience
Taxi (Fixed Fare)~$62 - $9920 - 40 minsSpeed & Ease
Shared Shuttle~$25 - $4045 - 75 minsDoor-to-Door Value

Note: Travel times can be heavily affected by traffic, especially during morning (7:00 AM - 9:30 AM) and evening (4:00 PM - 6:30 PM) peak hours.

Visitor Tip: Always ask for a fixed fare or flat rate to the city before you get in. Metered fares can be much more expensive (up to $90-$100+ in bad traffic).

Further information on these transport options is available in the following places:

Accommodation

Accommodation has been combined with the Human Digital Twin meetings and information on accommodation can be found there.

Human Digital Twin meetings accommodation information

Meals

Meals during the day for Harmony 2026 will be provided in coordination with the other digital twins meetings. For evening meals there is a great selection of a wide variety of restaurants a short walk or short taxi/Uber from the conference location.

Power outlet

Type I plugs are used in New Zealand, featuring three flat pins arranged in a triangular pattern. They operate on a voltage of 230V and are designed to ensure safety with an earth pin for grounding.

Plugs used in New Zealand (Wikipedia).

New Zealand power plugs

Registration

There is a NZ$640.00 registration fee for in-person attendess, please use the links available in the registration form to pay via Eventbrite and sign up for any add-on activities. For virtual attendess, there is no fee but you do need to register. Also, please register using the link provided as soon as possible. This will help us plan the schedule and match your interests to the timing of the breakouts, etc. Note, only registered attendees will be sent information related to the meeting.

Call for Breakout Sessions and Tutorials

All attendees can suggest breakout sessions for hacking and/or detailed discussions of certain aspects of one or several of the COMBINE standard(s), metadata and semantic annotations (format-specific or overarching), application and implementations of the COMBINE standards, or any other topic relevant for the COMBINE community. The topics for those breakout sessions, and the time slots which would suit their communities can be submitted via the link above. Note, breakout session organisers will be responsible for creating and hosting their own online sessions, if required.

Call for Lightning Talks and Posters

Requests for a lightning talk (5 min max.) and/or poster can be submitted via the link above. Please make multiple submissions if you want to submit abstracts on different topics. Talks will take place during the community session and posters will be displayed throughout the meeting.

Topics of Interest

  • Data exchange, pipelines and model standards for systems and synthetic biology
  • Visualisation and graphical notation standards for systems and synthetic biology
  • Standards for sharing and analysing biological pathway data
  • Standards for computational biological models and modelling support
  • Metadata description and model annotation in COMBINE standard formats
  • Implementation of COMBINE standards in tools, databases and other resources
  • Integrated model and data management for systems and synthetic biology
  • Standardization of Artificial Intelligence approaches in biological modelling
  • Emerging standardization needs and multicellular modeling
  • Community aspects of COMBINE